Tim Andrews, from New Hampshire, was suffering from end-stage kidney disease linked to type 2 diabetes when he underwent the pioneering procedure in the United States in January 2025. The genetically engineered organ was taken from a Yucatan miniature pig and modified to make it more compatible with the human immune system.
In what doctors are calling a major breakthrough in organ transplantation, a 66-year-old man has lived for 271 days without dialysis after receiving a genetically modified pig kidney, marking the longest known period a living human has remained dialysis-free following a pig-to-human kidney transplant.
Tim Andrews, from New Hampshire, was suffering from end-stage kidney disease linked to type 2 diabetes when he underwent the pioneering procedure in the United States in January 2025. The genetically engineered organ was taken from a Yucatan miniature pig and modified to make it more compatible with the human immune system.
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For Andrews, the experimental transplant was never intended to be a permanent replacement. Instead, doctors viewed the pig kidney as a temporary bridge that could keep him alive and functioning while he waited for a suitable human organ.
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