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OpenAI's CEO Of Applications Fidji Simo To Step Down Amid Health Struggles
24htopnews | July 11, 2026 8:08 PM CST

OpenAI CEO of AGI deployment Fidji Simo is stepping down from her full-time role after a three-month medical leave and will join as a part-time adviser. Simo said her recovery from a chronic condition diagnosed as POTS would require more time. Her responsibilities will be divided among other OpenAI executives.

Fidji Simo, OpenAI's No. 2 executive, is stepping down from her full-time role at the company. Simo, OpenAI's CEO of artificial general intelligence deployment, said in a note on X on Thursday that she will step down following a three-month medical leave. She will move into a part-time advisory role instead.

Simo faces health struggles

Simo said she had to go on medical leave three months ago after a severe exacerbation of a chronic illness she has lived with for seven years. She was diagnosed with Postural Orthostatic Tachycardia Syndrome, or POTS, in 2019. POTS is a chronic condition affecting the autonomic nervous system.

Simo wrote that during her leave it became clear the road to recovery would be much longer and more complex than she had anticipated, and that she needed to focus on it fully. She added that she is only making the decision now because she failed to make it many times before.


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