McGill finds TNAP switch controls brown fat heat in mice
NewsBytes | May 20, 2026 8:39 PM CST
Study links TNAP to hypophosphatasia
Turns out, TNAP isn't just about fat burning: it's tied to bone health too.
By looking at data from 500,000 people, researchers found that changes in TNAP's glycerol pocket are linked to weaker bones and a rare bone disease called hypophosphatasia.
These insights could lead to easier treatments for weak bones and new ways to tackle obesity or diabetes by boosting the body's natural calorie-burning power.
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